When you’re trying out a new migraine medication, it’s important to know that it could be a day, a few weeks, or even a few months, before you know if the medication is working for you. Don’t get discouraged or give up too soon, you may be discarding potentially helpful medicine!

Most abortive, pain killing and rescue medications should be effective (or not) the first time you take one.

Preventive medications, however, are not so simple. Because the dosages of most anti-seizure or anti-depressant medications must be raised or lowered very slowly over an extended period of time, then maintained at a consistent dose for several weeks, it’s important to be patient.

Some medicines like Riboflavin need several months before results are typically seen.

Changing, adding or subtracting other medications, supplements or herbs in your treatment plan could also alter the effectiveness of your trial drug. Educate yourself about all the medications you’re taking and check with your doctor and pharmacist to ensure the best results.

If you have given up on many medications in only a few weeks, you may want to consider getting a second opinion, or consulting a headache specialist who might be able to better guide you as you try out different medications and treatments.

Remember, when managed correctly, even a failed trial is a success because you now know one thing that doesn’t work for you.

For more information, see WEGO Health's Migraine Dictionary

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